BDBM50140736 CHEMBL3754710::US10383880, Example 58

SMILES: CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCCC1

InChI Key: InChIKey=XYHYPUGXAKJICQ-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140736   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140736 (CHEMBL3754710 | US10383880, Example 58) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCCC1 Show InChI InChI=1S/C21H26N2O3S/c1-27(25,26)23(16-8-2-3-9-16)15-17(24)14-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h4-7,10-13,16-17,24H,2-3,8-9,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140736 (CHEMBL3754710 | US10383880, Example 58) Show SMILES CS(=O)(=O)N(CC(O)Cn1c2ccccc2c2ccccc12)C1CCCC1 Show InChI InChI=1S/C21H26N2O3S/c1-27(25,26)23(16-8-2-3-9-16)15-17(24)14-22-20-12-6-4-10-18(20)19-11-5-7-13-21(19)22/h4-7,10-13,16-17,24H,2-3,8-9,14-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	308	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair