BDBM50140889 CHEMBL3752502::US10383880, Example 33

SMILES: OC(CN1CCCCS1(=O)=O)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=KQSYLMFIQXXHQD-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140889 (CHEMBL3752502 | US10383880, Example 33) Show SMILES OC(CN1CCCCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C19H22N2O3S/c22-15(13-20-11-5-6-12-25(20,23)24)14-21-18-9-3-1-7-16(18)17-8-2-4-10-19(17)21/h1-4,7-10,15,22H,5-6,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140889 (CHEMBL3752502 | US10383880, Example 33) Show SMILES OC(CN1CCCCS1(=O)=O)Cn1c2ccccc2c2ccccc12 Show InChI InChI=1S/C19H22N2O3S/c22-15(13-20-11-5-6-12-25(20,23)24)14-21-18-9-3-1-7-16(18)17-8-2-4-10-19(17)21/h1-4,7-10,15,22H,5-6,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	173	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair