BDBM50140894 CHEMBL3754467::US10383880, Example 124

SMILES: CN1CCCN(CC(O)Cn2c3ccccc3c3ccccc23)S1(=O)=O

InChI Key: InChIKey=MZZYNDIMZODFGH-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50140894   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140894 (CHEMBL3754467 | US10383880, Example 124) Show SMILES CN1CCCN(CC(O)Cn2c3ccccc3c3ccccc23)S1(=O)=O Show InChI InChI=1S/C19H23N3O3S/c1-20-11-6-12-21(26(20,24)25)13-15(23)14-22-18-9-4-2-7-16(18)17-8-3-5-10-19(17)22/h2-5,7-10,15,23H,6,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	154	n/a	n/a	n/a	n/a
Synchronicity US Patent					Assay Description Per2 Assay for Evaluating the Potency of Test Compounds.				US Patent US10383880 (2019) BindingDB Entry DOI: 10.7270/Q2J67K8X
					More data for this Ligand-Target Pair
Period circadian protein homolog 2 (Homo sapiens (Human))	BDBM50140894 (CHEMBL3754467 | US10383880, Example 124) Show SMILES CN1CCCN(CC(O)Cn2c3ccccc3c3ccccc23)S1(=O)=O Show InChI InChI=1S/C19H23N3O3S/c1-20-11-6-12-21(26(20,24)25)13-15(23)14-22-18-9-4-2-7-16(18)17-8-3-5-10-19(17)22/h2-5,7-10,15,23H,6,11-14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	726	n/a	n/a	n/a	n/a
Reset Therapeutics Curated by ChEMBL					Assay Description Reduction of amplitude effect of PER2 in human U2OS cells harboring Per2-dLuc luciferase reporter gene assessed as effects on circadian rhythms				Bioorg Med Chem Lett 26: 757-60 (2016) BindingDB Entry DOI: 10.7270/Q2DR2XCS
					More data for this Ligand-Target Pair