BDBM50140935 CHEMBL3753380

SMILES: N#C\C(=C/c1cccnc1)c1c[nH]c2ccc(OCc3ccccc3)cc12

InChI Key: InChIKey=XKSALERPZXDXPJ-YBFXNURJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50140935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kinesin-like protein KIF20A (Homo sapiens (Human))	BDBM50140935 (CHEMBL3753380) Show SMILES N#C\C(=C/c1cccnc1)c1c[nH]c2ccc(OCc3ccccc3)cc12 Show InChI InChI=1S/C23H17N3O/c24-13-19(11-18-7-4-10-25-14-18)22-15-26-23-9-8-20(12-21(22)23)27-16-17-5-2-1-3-6-17/h1-12,14-15,26H,16H2/b19-11+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
CNRS Curated by ChEMBL					Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr...				Bioorg Med Chem 24: 721-34 (2016) BindingDB Entry DOI: 10.7270/Q29025NR
					More data for this Ligand-Target Pair