BDBM50141067 3-[4-(2,4-Difluoro-phenoxy)-phenyl]-pyrazole-1-carboxylic acid amide::CHEMBL38401

SMILES: NC(=O)n1ccc(n1)-c1ccc(Oc2ccc(F)cc2F)cc1

InChI Key: InChIKey=OYOZIANRHNFTPI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4) (Homo sapiens (Human))	BDBM50141067 (3-[4-(2,4-Difluoro-phenoxy)-phenyl]-pyrazole-1-car...) Show SMILES NC(=O)n1ccc(n1)-c1ccc(Oc2ccc(F)cc2F)cc1 Show InChI InChI=1S/C16H11F2N3O2/c17-11-3-6-15(13(18)9-11)23-12-4-1-10(2-5-12)14-7-8-21(20-14)16(19)22/h1-9H,(H2,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Affinity for inactive human SkM1 sodium channel expressed in HEK293 cells				J Med Chem 47: 1547-52 (2004) Article DOI: 10.1021/jm030498q BindingDB Entry DOI: 10.7270/Q2SX6F0Q
					More data for this Ligand-Target Pair