BDBM50141117 (S)-2-[4-Diisopropylcarbamoyl-2-(naphthalen-1-yloxy)-benzoylamino]-4-methyl-pentanoic acid::CHEMBL28478

SMILES: CC(C)C[C@H](NC(=O)c1ccc(cc1Oc1cccc2ccccc12)C(=O)N(C(C)C)C(C)C)C(O)=O

InChI Key: InChIKey=PLUHAFCOXWJCJG-VWLOTQADSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM50141117 ((S)-2-[4-Diisopropylcarbamoyl-2-(naphthalen-1-ylox...) Show SMILES CC(C)C[C@H](NC(=O)c1ccc(cc1Oc1cccc2ccccc12)C(=O)N(C(C)C)C(C)C)C(O)=O Show InChI InChI=1S/C30H36N2O5/c1-18(2)16-25(30(35)36)31-28(33)24-15-14-22(29(34)32(19(3)4)20(5)6)17-27(24)37-26-13-9-11-21-10-7-8-12-23(21)26/h7-15,17-20,25H,16H2,1-6H3,(H,31,33)(H,35,36)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptide				Bioorg Med Chem Lett 14: 1375-9 (2004) Article DOI: 10.1016/j.bmcl.2003.09.096 BindingDB Entry DOI: 10.7270/Q2D799V3
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