null

SMILES: CN(C)CCOc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N

InChI Key: InChIKey=OCSKDLSKHJPMJJ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141150 (4-(3-Chloro-4-fluoro-phenylamino)-6-(2-dimethylami...) Show SMILES CN(C)CCOc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N Show InChI InChI=1S/C19H17ClFN5O/c1-26(2)5-6-27-18-8-14-17(11-24-18)23-10-12(9-22)19(14)25-13-3-4-16(21)15(20)7-13/h3-4,7-8,10-11H,5-6H2,1-2H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of epidermal growth factor receptor kinase autophosphorylation				Bioorg Med Chem Lett 14: 1411-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.034 BindingDB Entry DOI: 10.7270/Q2G161DC
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141150 (4-(3-Chloro-4-fluoro-phenylamino)-6-(2-dimethylami...) Show SMILES CN(C)CCOc1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N Show InChI InChI=1S/C19H17ClFN5O/c1-26(2)5-6-27-18-8-14-17(11-24-18)23-10-12(9-22)19(14)25-13-3-4-16(21)15(20)7-13/h3-4,7-8,10-11H,5-6H2,1-2H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of peptide substrate phosphorylation by epidermal growth factor receptor				Bioorg Med Chem Lett 14: 1411-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.034 BindingDB Entry DOI: 10.7270/Q2G161DC
					More data for this Ligand-Target Pair