null
SMILES: CC1C=C(NC(=O)C2=CC(NC(=O)C3=CC(NC(=O)c4ccc(cc4)C(=O)NC4=CC(C)C(=C4)C(=O)NC4=CC(C)C(=C4)C(=O)NC4=CC(C)C(=C4)C(=O)NCCC(N)=N)=CC3C)=CC2C)C=C1C(=O)NCCC(N)=N
InChI Key: InChIKey=QECKQKHUNCHMGA-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Integrase (Human immunodeficiency virus 1) | BDBM50141236 (CHEMBL216058 | N,N'-Bis-(4-{4-[4-(2-carbamimidoyl-...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Houston Curated by ChEMBL | Assay Description Inhibitory activity against HIV-1 integrase | Bioorg Med Chem Lett 14: 1447-54 (2004) Article DOI: 10.1016/j.bmcl.2004.01.027 BindingDB Entry DOI: 10.7270/Q2B858PN | |||||||||||
More data for this Ligand-Target Pair |