BDBM50141306 CHEMBL286394::N-[4-Chloro-3-(5-chloro-benzothiazol-2-yl)-phenyl]-2-cyano-acetamide

SMILES: Clc1ccc2sc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl

InChI Key: InChIKey=FVAAHBHWXQJFLG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
1-acylglycerol-3-phosphate O-acyltransferase beta (Homo sapiens (Human))	BDBM50141306 (CHEMBL286394 | N-[4-Chloro-3-(5-chloro-benzothiazo...) Show SMILES Clc1ccc2sc(nc2c1)-c1cc(NC(=O)CC#N)ccc1Cl Show InChI InChI=1S/C16H9Cl2N3OS/c17-9-1-4-14-13(7-9)21-16(23-14)11-8-10(2-3-12(11)18)20-15(22)5-6-19/h1-4,7-8H,5H2,(H,20,22)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Cell Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against human lysophosphatidic acid acyltransferase-beta (LPAAT-beta) expressed in Sf9 insect cell membranes				Bioorg Med Chem Lett 14: 1455-9 (2004) Article DOI: 10.1016/j.bmcl.2004.01.023 BindingDB Entry DOI: 10.7270/Q20Z72Q5
					More data for this Ligand-Target Pair