BDBM50141524 (E)-1-[4-(3,4-Dimethoxy-benzyloxy)-3,5-dimethoxy-phenyl]-3-(3,4,5-trimethoxy-phenyl)-propenone::CHEMBL285544

SMILES: COc1ccc(COc2c(OC)cc(cc2OC)C(=O)\C=C\c2cc(OC)c(OC)c(OC)c2)cc1OC

InChI Key: InChIKey=BEMRFGULJPGXCL-CSKARUKUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141524   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50141524 ((E)-1-[4-(3,4-Dimethoxy-benzyloxy)-3,5-dimethoxy-p...) Show SMILES COc1ccc(COc2c(OC)cc(cc2OC)C(=O)\C=C\c2cc(OC)c(OC)c(OC)c2)cc1OC Show InChI InChI=1S/C29H32O9/c1-31-22-11-9-19(14-23(22)32-2)17-38-29-26(35-5)15-20(16-27(29)36-6)21(30)10-8-18-12-24(33-3)28(37-7)25(13-18)34-4/h8-16H,17H2,1-7H3/b10-8+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AtheroGenics, Inc. Curated by ChEMBL					Assay Description Inhibition of TNF-alpha-induced VCAM-1 expression				Bioorg Med Chem Lett 14: 1513-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.021 BindingDB Entry DOI: 10.7270/Q2028QZK
					More data for this Ligand-Target Pair