BDBM50141549 (E)-3-(5-Bromo-2,4-dimethoxy-phenyl)-1-(3,4,5-trimethoxy-phenyl)-propenone::CHEMBL37200

SMILES: COc1cc(OC)c(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Br

InChI Key: InChIKey=NKFRYLBKSHPAPG-VOTSOKGWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor receptor R1 (Homo sapiens (Human))	BDBM50141549 ((E)-3-(5-Bromo-2,4-dimethoxy-phenyl)-1-(3,4,5-trim...) Show SMILES COc1cc(OC)c(\C=C\C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Br Show InChI InChI=1S/C20H21BrO6/c1-23-16-11-17(24-2)14(21)8-12(16)6-7-15(22)13-9-18(25-3)20(27-5)19(10-13)26-4/h6-11H,1-5H3/b7-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AtheroGenics, Inc. Curated by ChEMBL					Assay Description Inhibition of TNF-alpha-induced VCAM-1 expression				Bioorg Med Chem Lett 14: 1513-7 (2004) Article DOI: 10.1016/j.bmcl.2004.01.021 BindingDB Entry DOI: 10.7270/Q2028QZK
					More data for this Ligand-Target Pair