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SMILES: CCOc1c(cc(cc1-c1cccc2cc(sc12)C(\C)=C\C(O)=O)C(C)C)C(C)C
InChI Key: InChIKey=ROMUEEKDVNXHBX-GZTJUZNOSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50141593 ((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 271 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against Retinoic acid receptor RXR-alpha by [3H]-9-cis-RA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Retinoic acid receptor RXR-beta (Mus musculus) | BDBM50141593 ((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity again retinoic acid receptor beta by [3H]-ATRA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Retinoic acid receptor alpha (Homo sapiens (Human)) | BDBM50141593 ((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against retinoic acid receptor alpha by [3H]-ATRA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Retinoic acid receptor RXR-gamma (Mus musculus) | BDBM50141593 ((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Binding affinity against retinoic acid receptor gamma by [3H]-ATRA displacement. | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Retinoic acid receptor RXR-alpha (Homo sapiens (Human)) | BDBM50141593 ((E)-3-[7-(2-Ethoxy-3,5-diisopropyl-phenyl)-benzo[b...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 390 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals Inc Curated by ChEMBL | Assay Description Transcriptional activation in CV-1 cells expressing Retinoid X receptor alpha | Bioorg Med Chem Lett 14: 1593-8 (2004) Article DOI: 10.1016/j.bmcl.2003.12.089 BindingDB Entry DOI: 10.7270/Q2B857JF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
