BindingDB logo
myBDB logout

null

SMILES: CC1(C)OCc2c1nc(nc2Nc1n[nH]c(Cl)c1Cl)-c1cn[nH]c1

InChI Key: InChIKey=JCYJEGMUKHOEDZ-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141647   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2/Receptor tyrosine-protein kinase erbB-3/Receptor tyrosine-protein kinase erbB-4


(Homo sapiens (Human))		BDBM50141647
PNG
(CHEMBL3758646)
Show SMILES CC1(C)OCc2c1nc(nc2Nc1n[nH]c(Cl)c1Cl)-c1cn[nH]c1
Show InChI InChI=1S/C14H13Cl2N7O/c1-14(2)9-7(5-24-14)12(21-13-8(15)10(16)22-23-13)20-11(19-9)6-3-17-18-4-6/h3-4H,5H2,1-2H3,(H,17,18)(H2,19,20,21,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
 389n/an/an/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of EGFR T790M/L858R mutant (unknown origin)

Bioorg Med Chem Lett 26: 534-9 (2016)


BindingDB Entry DOI: 10.7270/Q2HH6MZQ
More data for this
Ligand-Target Pair