BDBM50141657 CHEMBL3758958

SMILES: CC1(C)OCc2c1nc(nc2Nc1c[nH]c2ccccc12)-c1cn[nH]c1

InChI Key: InChIKey=RMKXHEPYDGCAAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141657   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141657 (CHEMBL3758958) Show SMILES CC1(C)OCc2c1nc(nc2Nc1c[nH]c2ccccc12)-c1cn[nH]c1 Show InChI InChI=1S/C19H18N6O/c1-19(2)16-13(10-26-19)18(25-17(24-16)11-7-21-22-8-11)23-15-9-20-14-6-4-3-5-12(14)15/h3-9,20H,10H2,1-2H3,(H,21,22)(H,23,24,25)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin)				Bioorg Med Chem Lett 26: 534-9 (2016) BindingDB Entry DOI: 10.7270/Q2HH6MZQ
					More data for this Ligand-Target Pair