BDBM50141670 CHEMBL3758948

SMILES: CC1(C)OCc2c1nc(nc2Nc1n[nH]c2c(cccc12)C(F)(F)F)-c1cn[nH]c1

InChI Key: InChIKey=WRTRKQNELWWYGA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50141670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50141670 (CHEMBL3758948) Show SMILES CC1(C)OCc2c1nc(nc2Nc1n[nH]c2c(cccc12)C(F)(F)F)-c1cn[nH]c1 Show InChI InChI=1S/C19H16F3N7O/c1-18(2)14-11(8-30-18)16(26-15(25-14)9-6-23-24-7-9)27-17-10-4-3-5-12(19(20,21)22)13(10)28-29-17/h3-7H,8H2,1-2H3,(H,23,24)(H2,25,26,27,28,29)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	134	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin)				Bioorg Med Chem Lett 26: 534-9 (2016) BindingDB Entry DOI: 10.7270/Q2HH6MZQ
					More data for this Ligand-Target Pair