BDBM50142028 CHEMBL3758700

SMILES: CC1(C)OCc2c1nc(nc2Nc1n[nH]c2c(Cl)c(F)ccc12)-c1cn[nH]c1

InChI Key: InChIKey=XXKKLMVAVKRRTQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142028   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50142028 (CHEMBL3758700) Show SMILES CC1(C)OCc2c1nc(nc2Nc1n[nH]c2c(Cl)c(F)ccc12)-c1cn[nH]c1 Show InChI InChI=1S/C18H15ClFN7O/c1-18(2)14-10(7-28-18)16(24-15(23-14)8-5-21-22-6-8)25-17-9-3-4-11(20)12(19)13(9)26-27-17/h3-6H,7H2,1-2H3,(H,21,22)(H2,23,24,25,26,27)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Inhibition of EGFR T790M/L858R mutant (unknown origin)				Bioorg Med Chem Lett 26: 534-9 (2016) BindingDB Entry DOI: 10.7270/Q2HH6MZQ
					More data for this Ligand-Target Pair