BDBM50142074 CHEMBL3758342

SMILES: Cc1ccc(cc1)-c1ncc(OCc2ccccc2)cc1-c1ccc(cc1)C#N

InChI Key: InChIKey=BLYCHICSICYTJE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142074   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142074 (CHEMBL3758342) Show SMILES Cc1ccc(cc1)-c1ncc(OCc2ccccc2)cc1-c1ccc(cc1)C#N Show InChI InChI=1S/C26H20N2O/c1-19-7-11-23(12-8-19)26-25(22-13-9-20(16-27)10-14-22)15-24(17-28-26)29-18-21-5-3-2-4-6-21/h2-15,17H,18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair