BDBM50142117 2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(5-bromo-pyridin-2-ylcarbamoyl)-4-(4-methyl-piperazin-1-yl)-phenyl]-amide::CHEMBL435525

SMILES: CN1CCN(CC1)c1ccc(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c(c1)C(=O)Nc1ccc(Br)cn1

InChI Key: InChIKey=WIWDJWUWHPRFSL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50142117 (2'-Sulfamoyl-biphenyl-4-carboxylic acid [2-(5-brom...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2ccc(cc2)-c2ccccc2S(N)(=O)=O)c(c1)C(=O)Nc1ccc(Br)cn1 Show InChI InChI=1S/C30H29BrN6O4S/c1-36-14-16-37(17-15-36)23-11-12-26(25(18-23)30(39)35-28-13-10-22(31)19-33-28)34-29(38)21-8-6-20(7-9-21)24-4-2-3-5-27(24)42(32,40)41/h2-13,18-19H,14-17H2,1H3,(H,34,38)(H2,32,40,41)(H,33,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against coagulation factor Xa.				Bioorg Med Chem Lett 14: 983-7 (2004) Article DOI: 10.1016/j.bmcl.2003.11.079 BindingDB Entry DOI: 10.7270/Q21V5DF7
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