BDBM50142133 3'-Pyrrolidin-1-yl-biphenyl-4-carboxylic acid [4-chloro-2-(5-chloro-pyridin-2-ylcarbamoyl)-phenyl]-amide::CHEMBL176830

SMILES: Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2cccc(c2)N2CCCC2)nc1

InChI Key: InChIKey=QVPBCWZFUHMPKO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142133   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50142133 (3'-Pyrrolidin-1-yl-biphenyl-4-carboxylic acid [4-c...) Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(cc2)-c2cccc(c2)N2CCCC2)nc1 Show InChI InChI=1S/C29H24Cl2N4O2/c30-22-10-12-26(25(17-22)29(37)34-27-13-11-23(31)18-32-27)33-28(36)20-8-6-19(7-9-20)21-4-3-5-24(16-21)35-14-1-2-15-35/h3-13,16-18H,1-2,14-15H2,(H,33,36)(H,32,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibitory concentration against coagulation factor Xa.				Bioorg Med Chem Lett 14: 983-7 (2004) Article DOI: 10.1016/j.bmcl.2003.11.079 BindingDB Entry DOI: 10.7270/Q21V5DF7
					More data for this Ligand-Target Pair