Found 6 hits for monomerid = 50142152 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Plasminogen
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against plasmin. |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
Tissue-type plasminogen activator
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against tissue type plasminogen activator. |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
Vitamin K-dependent protein C
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against activated protein C |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
Trypsin-1
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against trypsin. |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
Coagulation factor X
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
In vitro inhibitory activity against coagulation factor X. |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
Prothrombin
(Homo sapiens (Human)) | BDBM50142152
(5-Chloro-N-(5-chloro-pyridin-2-yl)-2-(4-piperidin-...)Show SMILES Clc1ccc(NC(=O)c2cc(Cl)ccc2NC(=O)c2ccc(CN3CCCCC3)cc2)nc1 Show InChI InChI=1S/C25H24Cl2N4O2/c26-19-8-10-22(21(14-19)25(33)30-23-11-9-20(27)15-28-23)29-24(32)18-6-4-17(5-7-18)16-31-12-2-1-3-13-31/h4-11,14-15H,1-3,12-13,16H2,(H,29,32)(H,28,30,33) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibitory activity against thrombin. |
Bioorg Med Chem Lett 14: 989-93 (2004)
Article DOI: 10.1016/j.bmcl.2003.11.080
BindingDB Entry DOI: 10.7270/Q2X34WXD |
More data for this
Ligand-Target Pair | |
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