BDBM50142188 CHEMBL3759472

SMILES: N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccncc1

InChI Key: InChIKey=VINZQFMCUKWAFJ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50142188 (CHEMBL3759472) Show SMILES N#Cc1ccc(cc1)-c1cc(OCC2CCNCC2)cnc1-c1ccncc1 Show InChI InChI=1S/C23H22N4O/c24-14-17-1-3-19(4-2-17)22-13-21(28-16-18-5-9-25-10-6-18)15-27-23(22)20-7-11-26-12-8-20/h1-4,7-8,11-13,15,18,25H,5-6,9-10,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Baylor College of Medicine Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...				J Med Chem 59: 253-63 (2016) BindingDB Entry DOI: 10.7270/Q23J3FSW
					More data for this Ligand-Target Pair