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BDBM50142236 CHEMBL3760085

SMILES: Fc1ccc(c(F)c1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(cc1)C#N

InChI Key: InChIKey=GIWNHKHXEFMPSG-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142236   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific histone demethylase 1A


(Homo sapiens (Human))		BDBM50142236
PNG
(CHEMBL3760085)
Show SMILES Fc1ccc(c(F)c1)-c1ncc(OCC2CCNCC2)cc1-c1ccc(cc1)C#N
Show InChI InChI=1S/C24H21F2N3O/c25-19-5-6-21(23(26)11-19)24-22(18-3-1-16(13-27)2-4-18)12-20(14-29-24)30-15-17-7-9-28-10-8-17/h1-6,11-12,14,17,28H,7-10,15H2
PDB
MMDB

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PC cid
PC sid
UniChem
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Baylor College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of recombinant human GST-tagged LSD1 catalytic domain (172 to 833 residues) using dimethylated H3K4 peptide substrate preincubated for 10 ...

J Med Chem 59: 253-63 (2016)


BindingDB Entry DOI: 10.7270/Q23J3FSW
More data for this
Ligand-Target Pair