BDBM50142500 (2S)-2-amino-4-(methylsulfanyl)butanoic acid::(S)-2-amino-4-(methylthio)butanoic acid::(S)-2-amino-4-(methylthio)butyric acid::(S)-methionine::CHEMBL42336::L-(-)-methionine::L-Methionin::L-alpha-amino-gamma-methylmercaptobutyric acid::L-methionine
SMILES: CSCC[C@H](N)C(O)=O
InChI Key: InChIKey=FFEARJCKVFRZRR-BYPYZUCNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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S-ribosylhomocysteine lyase (Bacillus subtilis) | BDBM50142500 ((2S)-2-amino-4-(methylsulfanyl)butanoic acid | (S)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Ohio State University Curated by ChEMBL | Assay Description Inhibition of cobalt substituted Bacillus subtilis LuxS | J Med Chem 49: 3003-11 (2006) Article DOI: 10.1021/jm060047g BindingDB Entry DOI: 10.7270/Q25X28JQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-glutamyltranspeptidase 1 (Rattus norvegicus) | BDBM50142500 ((2S)-2-amino-4-(methylsulfanyl)butanoic acid | (S)...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.69E+7 | n/a | n/a | n/a | n/a | n/a | n/a | 8.0 | n/a |
Universit£ de Montr£al Curated by ChEMBL | Assay Description Compound tested for the inhibition of Gamma-glutamyltranspeptidase in rat kidney at pH 8.0 at 37 degree C (Competitive inhibition) | Bioorg Med Chem Lett 14: 3451-5 (2004) Article DOI: 10.1016/j.bmcl.2004.04.072 BindingDB Entry DOI: 10.7270/Q2X63NHS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid synthase (Homo sapiens (Human)) | BDBM50142500 ((2S)-2-amino-4-(methylsulfanyl)butanoic acid | (S)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.50E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Pierre et Marie Curie Curated by ChEMBL | Assay Description Inhibition constant against Escherichia coli cyclopropane fatty acid synthase | Bioorg Med Chem Lett 14: 1661-4 (2004) Article DOI: 10.1016/j.bmcl.2004.01.051 BindingDB Entry DOI: 10.7270/Q26H4HZX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Xanthine dehydrogenase (Homo sapiens (Human)) | BDBM50142500 ((2S)-2-amino-4-(methylsulfanyl)butanoic acid | (S)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | >6.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CHINA PHARMACEUTICAL UNIVERSITY US Patent | Assay Description 11.1 Preparation of Reagents and Standard Solutions(1) 75 mM phosphate buffer (PB, pH 7.4): containing KH2PO4 0.0956 g, K2HPO4 0.6946 g, EDTA 1.862 m... | US Patent US11021454 (2021) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Large neutral amino acids transporter small subunit 1 (Homo sapiens (Human)) | BDBM50142500 ((2S)-2-amino-4-(methylsulfanyl)butanoic acid | (S)...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California Curated by ChEMBL | Assay Description Cis-inhibition of human LAT1 expressed in TREx HEK293 cells at 200 uM assessed as inhibition of [3H]-gabapentin uptake preincubated for 3 mins at 37 ... | J Med Chem 61: 7358-7373 (2018) Article DOI: 10.1021/acs.jmedchem.8b01007 BindingDB Entry DOI: 10.7270/Q2XK8J66 | |||||||||||
More data for this Ligand-Target Pair |