BDBM50142512 CHEMBL296797::N-(2-Benzoylamino-4-hydroxyphenyl)-4-hydroxy-benzamide

SMILES: Oc1ccc(cc1)C(=O)Nc1ccccc1NC(=O)c1ccc(O)cc1

InChI Key: InChIKey=AJKDXRGCWFSRHR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50142512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase I (Topo I) (Homo sapiens (Human))	BDBM50142512 (CHEMBL296797 | N-(2-Benzoylamino-4-hydroxyphenyl)-...) Show SMILES Oc1ccc(cc1)C(=O)Nc1ccccc1NC(=O)c1ccc(O)cc1 Show InChI InChI=1S/C20H16N2O4/c23-15-9-5-13(6-10-15)19(25)21-17-3-1-2-4-18(17)22-20(26)14-7-11-16(24)12-8-14/h1-12,23-24H,(H,21,25)(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto University Curated by ChEMBL					Assay Description Inhibitory concentration against relaxation activity of DNA topoisomerase I by detecting the conversion of supercoiled pBR322 DNA to its relaxed form				Bioorg Med Chem Lett 14: 1669-72 (2004) Article DOI: 10.1016/j.bmcl.2004.01.060 BindingDB Entry DOI: 10.7270/Q2GX4B0X
					More data for this Ligand-Target Pair