BDBM50142684 CHEMBL1651446
SMILES: ClCC(=O)N1c2ccccc2Sc2ccccc12
InChI Key: InChIKey=NVRFGQJNKQLUPU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypanothione Reductase (TryR) (Trypanosoma brucei brucei) | BDBM50142684 (CHEMBL1651446) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Wuerzburg Curated by ChEMBL | Assay Description Time dependent inhibition of recombinant Trypanosoma brucei trypanothione reductase preincubated with protein for 10 to 180 mins followed by NADPH, t... | Eur J Med Chem 108: 436-43 (2016) BindingDB Entry DOI: 10.7270/Q2GH9KTB | |||||||||||
More data for this Ligand-Target Pair |