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BDBM50142961 CHEMBL3758715

SMILES: CCCCc1ccc(cc1)-c1cccc(n1)-c1noc(Cc2c[nH]c3ccccc23)n1

InChI Key: InChIKey=KEXJXKNMHCJGSP-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50142961
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50142961 (CHEMBL3758715) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP1B catalytic domain assessed as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1C (Homo sapiens (Human))	BDBM50142961 (CHEMBL3758715) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human SHP1 as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein phosphatase F (LAR) (Homo sapiens (Human))	BDBM50142961 (CHEMBL3758715) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human LAR as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50142961 (CHEMBL3758715) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human TCPTP as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 11 (Homo sapiens (Human))	BDBM50142961 (CHEMBL3758715) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Materia Medica Curated by ChEMBL					Assay Description Inhibition of human SHP2 as hydrolysis of pNPP after 2 mins				Bioorg Med Chem Lett 26: 778-81 (2016) BindingDB Entry DOI: 10.7270/Q2K939CS
Shanghai Institute of Materia Medica Curated by ChEMBL					More data for this Ligand-Target Pair