BDBM50143039 8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]-3-phenyl-(1R)-propyl]-2'-benzo[d][1,3]dioxol-5-ylmethyl-1',3'-dioxospiro[hexahydropyridine-4,5'-perhydro[1,2,4]triazolo[1,2-a]pyridazine]-8'-carboxamide::CHEMBL298224
SMILES: NC(=O)[C@@H](CCc1ccccc1)NC(=O)[C@@H](CCc1ccccc1)NC(=O)C1CCC2(CCNCC2)n2n1c(=O)n(Cc1ccc3OCOc3c1)c2=O
InChI Key: InChIKey=PFKVNFAOBMPXFV-KCUXUGRMSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Motilin receptor (Homo sapiens (Human)) | BDBM50143039 (8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro binding affinity towards human motilin receptor | J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Motilin receptor (Homo sapiens (Human)) | BDBM50143039 (8'N-[1-[1-carbamoyl-3-phenyl-(1R)-propylcarbamoyl]...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description In vitro effective concentration towards human motilin receptor | J Med Chem 47: 1704-8 (2004) Article DOI: 10.1021/jm0304865 BindingDB Entry DOI: 10.7270/Q2571CRC | |||||||||||
More data for this Ligand-Target Pair |