BDBM50143070 (S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-tetrazol-5-yl]-propyl}-ureido)-pentanedioic acid::CHEMBL47058

SMILES: OC(=O)CC[C@H](NC(=O)N[C@@H](CCc1nnnn1CCC#N)C(O)=O)C(O)=O

InChI Key: InChIKey=QHBSOTRRIAYMOD-IUCAKERBSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAALADase II (Homo sapiens (Human))	BDBM50143070 ((S)-2-(3-{(S)-1-Carboxy-3-[1-(2-cyano-ethyl)-1H-te...) Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCc1nnnn1CCC#N)C(O)=O)C(O)=O Show InChI InChI=1S/C14H19N7O7/c15-6-1-7-21-10(18-19-20-21)4-2-8(12(24)25)16-14(28)17-9(13(26)27)3-5-11(22)23/h8-9H,1-5,7H2,(H,22,23)(H,24,25)(H,26,27)(H2,16,17,28)/t8-,9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description In vitro inhibitory activity against human Glutamate carboxypeptidase II by using fluorescent assay				J Med Chem 47: 1729-38 (2004) Article DOI: 10.1021/jm0306226 BindingDB Entry DOI: 10.7270/Q2DZ07RR
					More data for this Ligand-Target Pair