BDBM50143219 CHEMBL3758418

SMILES: Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3ncccn3)c2)n1

InChI Key: InChIKey=YQANMBGICJVOQZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143219 (CHEMBL3758418) Show SMILES Cn1cc(cn1)-c1ccc(=O)n(Cc2cccc(Nc3ncccn3)c2)n1 Show InChI InChI=1S/C19H17N7O/c1-25-13-15(11-22-25)17-6-7-18(27)26(24-17)12-14-4-2-5-16(10-14)23-19-20-8-3-9-21-19/h2-11,13H,12H2,1H3,(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair