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BDBM50143254 CHEMBL3758597

SMILES: Cn1cc(cn1)-c1ccnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)n1

InChI Key: InChIKey=ZPPSZAJURBXEBB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143254   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM50143254
PNG
(CHEMBL3758597)
Show SMILES Cn1cc(cn1)-c1ccnc(Nc2cccc(Cn3nc(ccc3=O)-c3cnn(C)c3)c2)n1
Show InChI InChI=1S/C23H21N9O/c1-30-14-17(11-25-30)20-8-9-24-23(28-20)27-19-5-3-4-16(10-19)13-32-22(33)7-6-21(29-32)18-12-26-31(2)15-18/h3-12,14-15H,13H2,1-2H3,(H,24,27,28)
PDB
MMDB

KEGG

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UniProtKB/TrEMBL

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PC cid
PC sid
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Similars
PubMed
n/an/a>100n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA

Eur J Med Chem 108: 322-33 (2016)


BindingDB Entry DOI: 10.7270/Q2DJ5HG7
More data for this
Ligand-Target Pair