BDBM50143257 CHEMBL3758452

SMILES: Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3ccc(Cl)c(c3)C(F)(F)F)c2)nc1

InChI Key: InChIKey=ZAAZRCOJDBRQBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143257   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143257 (CHEMBL3758452) Show SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3ccc(Cl)c(c3)C(F)(F)F)c2)nc1 Show InChI InChI=1S/C26H19ClF3N7O/c1-36-15-19(13-33-36)18-11-31-25(32-12-18)34-20-4-2-3-16(9-20)14-37-24(38)8-7-23(35-37)17-5-6-22(27)21(10-17)26(28,29)30/h2-13,15H,14H2,1H3,(H,31,32,34)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair