BDBM50143260 CHEMBL3758647

SMILES: Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cccc(c3)S(C)(=O)=O)c2)nc1

InChI Key: InChIKey=MAGQEQDAGPVXHL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143260   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50143260 (CHEMBL3758647) Show SMILES Cn1cc(cn1)-c1cnc(Nc2cccc(Cn3nc(ccc3=O)-c3cccc(c3)S(C)(=O)=O)c2)nc1 Show InChI InChI=1S/C26H23N7O3S/c1-32-17-21(15-29-32)20-13-27-26(28-14-20)30-22-7-3-5-18(11-22)16-33-25(34)10-9-24(31-33)19-6-4-8-23(12-19)37(2,35)36/h3-15,17H,16H2,1-2H3,(H,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant c-Met (unknown origin) using poly (Glu,Tyr)4:1 as substrate after 60 mins by ELISA				Eur J Med Chem 108: 322-33 (2016) BindingDB Entry DOI: 10.7270/Q2DJ5HG7
					More data for this Ligand-Target Pair