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BDBM50143311 (3aR,9bS)-1-Methyl-6-nonyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[2,3-f]quinolin-6-ium; iodide::(3aR,9bS)-1-methyl-6-nonyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[2,3-f]quinolin-6-ium iodide::CHEMBL54225

SMILES: CCCCCCCCC[n+]1cccc2[C@@H]3[C@@H](CCN3C)CCc12

InChI Key: InChIKey=JREBNQBVFKNXOB-NQIIRXRSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143311   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit


(Rattus norvegicus (Rat))		BDBM50143311
PNG
((3aR,9bS)-1-Methyl-6-nonyl-2,3,3a,4,5,9b-hexahydro...)
Show SMILES CCCCCCCCC[n+]1cccc2[C@@H]3[C@@H](CCN3C)CCc12
Show InChI InChI=1S/C21H35N2/c1-3-4-5-6-7-8-9-15-23-16-10-11-19-20(23)13-12-18-14-17-22(2)21(18)19/h10-11,16,18,21H,3-9,12-15,17H2,1-2H3/q+1/t18-,21+/m1/s1
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Similars
Article
PubMed
n/an/a 310n/an/an/an/an/an/a



University of Kentucky

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slices

Bioorg Med Chem Lett 14: 1869-74 (2004)


Article DOI: 10.1016/j.bmcl.2003.10.074
BindingDB Entry DOI: 10.7270/Q21N80JP
More data for this
Ligand-Target Pair