BDBM50143325 2-(6-Chloro-pyridin-3-yl)-7-ethyl-7-aza-bicyclo[2.2.1]heptane::CHEMBL57395

SMILES: CCN1C2CCC1C(C2)c1ccc(Cl)nc1

InChI Key: InChIKey=JQIIXRVNUHNTBY-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143325   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit (Rattus norvegicus (Rat))	BDBM50143325 (2-(6-Chloro-pyridin-3-yl)-7-ethyl-7-aza-bicyclo[2....) Show SMILES CCN1C2CCC1C(C2)c1ccc(Cl)nc1 |TLB:9:7:2:5.4,1:2:7.8:5.4| Show InChI InChI=1S/C13H17ClN2/c1-2-16-10-4-5-12(16)11(7-10)9-3-6-13(14)15-8-9/h3,6,8,10-12H,2,4-5,7H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 from rat membranes				Bioorg Med Chem Lett 14: 1889-96 (2004) Article DOI: 10.1016/j.bmcl.2004.02.007 BindingDB Entry DOI: 10.7270/Q2S75FR9
					More data for this Ligand-Target Pair