BDBM50143347 CHEMBL58047::N*1*,N*1*-Diethyl-N*4*-(1,2,3,4,5,6,7,8-octahydro-acridin-9-yl)-pentane-1,4-diamine

SMILES: CCN(CC)CCCC(C)Nc1c2CCCCc2nc2CCCCc12

InChI Key: InChIKey=YKORLKMHNGQVSH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50143347 (CHEMBL58047 | N*1*,N*1*-Diethyl-N*4*-(1,2,3,4,5,6,...) Show SMILES CCN(CC)CCCC(C)Nc1c2CCCCc2nc2CCCCc12 Show InChI InChI=1S/C22H37N3/c1-4-25(5-2)16-10-11-17(3)23-22-18-12-6-8-14-20(18)24-21-15-9-7-13-19(21)22/h17H,4-16H2,1-3H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)				Bioorg Med Chem Lett 14: 1913-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.087 BindingDB Entry DOI: 10.7270/Q2HQ3ZBQ
					More data for this Ligand-Target Pair