BDBM50143362 Acridin-9-yl-(1-methyl-4-pyrrolidin-1-yl-butyl)-amine::CHEMBL299681

SMILES: CC(CCCN1CCCC1)Nc1c2ccccc2nc2ccccc12

InChI Key: InChIKey=ADZYAMKAMJQCOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50143362 (Acridin-9-yl-(1-methyl-4-pyrrolidin-1-yl-butyl)-am...) Show SMILES CC(CCCN1CCCC1)Nc1c2ccccc2nc2ccccc12 Show InChI InChI=1S/C22H27N3/c1-17(9-8-16-25-14-6-7-15-25)23-22-18-10-2-4-12-20(18)24-21-13-5-3-11-19(21)22/h2-5,10-13,17H,6-9,14-16H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane)				Bioorg Med Chem Lett 14: 1913-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.087 BindingDB Entry DOI: 10.7270/Q2HQ3ZBQ
					More data for this Ligand-Target Pair