BDBM50143363 CHEMBL59367::N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-pentane-1,4-diamine
SMILES: CCN(CC)CCCC(C)Nc1c2ccccc2nc2ccccc12
InChI Key: InChIKey=QRPXUGKLXFUGCX-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Voltage-dependent calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human)) | BDBM50143363 (CHEMBL59367 | N*4*-Acridin-9-yl-N*1*,N*1*-diethyl-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane) | Bioorg Med Chem Lett 14: 1913-6 (2004) Article DOI: 10.1016/j.bmcl.2004.01.087 BindingDB Entry DOI: 10.7270/Q2HQ3ZBQ | |||||||||||
More data for this Ligand-Target Pair |