BDBM50143627 C,C,C-Trifluoro-N-{5-[2-(6-methoxy-quinolin-2-yl)-vinyl]-naphthalen-2-yl}-methanesulfonamide::CHEMBL433457

SMILES: COc1ccc2nc(\C=C\c3cccc4cc(NS(=O)(=O)C(F)(F)F)ccc34)ccc2c1

InChI Key: InChIKey=VNHDARHZIXCZOZ-FNORWQNLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50143627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)	BDBM50143627 (C,C,C-Trifluoro-N-{5-[2-(6-methoxy-quinolin-2-yl)-...) Show SMILES COc1ccc2nc(\C=C\c3cccc4cc(NS(=O)(=O)C(F)(F)F)ccc34)ccc2c1 Show InChI InChI=1S/C23H17F3N2O3S/c1-31-20-10-12-22-17(14-20)6-8-18(27-22)7-5-15-3-2-4-16-13-19(9-11-21(15)16)28-32(29,30)23(24,25)26/h2-14,28H,1H3/b7-5+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibitory concentration against HCMV protease.				J Med Chem 47: 1893-9 (2004) Article DOI: 10.1021/jm030540h BindingDB Entry DOI: 10.7270/Q2765DRK
					More data for this Ligand-Target Pair