BindingDB PrimarySearch

BDBM50143732 (2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL58577

SMILES: ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1

InChI Key: InChIKey=LQZDEWIIFWHTLX-BRSBDYLESA-N

Data: 4 KI 1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50143732
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50143732 ((2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center N-21 Curated by ChEMBL					Assay Description Inhibition of human tumor necrosis factor alpha converting enzyme				J Med Chem 47: 1930-8 (2004) Article DOI: 10.1021/jm0304313 BindingDB Entry DOI: 10.7270/Q2ZS2VXF
Hokkaido Collaboration Center N-21 Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50143732 ((2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center N-21 Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloprotease 3				J Med Chem 47: 1930-8 (2004) Article DOI: 10.1021/jm0304313 BindingDB Entry DOI: 10.7270/Q2ZS2VXF
Hokkaido Collaboration Center N-21 Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50143732 ((2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center N-21 Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloprotease 9				J Med Chem 47: 1930-8 (2004) Article DOI: 10.1021/jm0304313 BindingDB Entry DOI: 10.7270/Q2ZS2VXF
Hokkaido Collaboration Center N-21 Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50143732 ((2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center N-21 Curated by ChEMBL					Assay Description Inhibition of human recombinant matrix metalloprotease 1				J Med Chem 47: 1930-8 (2004) Article DOI: 10.1021/jm0304313 BindingDB Entry DOI: 10.7270/Q2ZS2VXF
Hokkaido Collaboration Center N-21 Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50143732 ((2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center N-21 Curated by ChEMBL					Assay Description Inhibition of heparin-binding HB-EGF shedding				J Med Chem 47: 1930-8 (2004) Article DOI: 10.1021/jm0304313 BindingDB Entry DOI: 10.7270/Q2ZS2VXF
Hokkaido Collaboration Center N-21 Curated by ChEMBL					More data for this Ligand-Target Pair