BDBM50143840 (S)-5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-3-methyl-5-oxo-pentanoic acid::CHEMBL62639

SMILES: C[C@H](CC(O)=O)CC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1

InChI Key: InChIKey=UKLBLFWTHWVCSP-AWEZNQCLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143840   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143840 ((S)-5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-...) Show SMILES C[C@H](CC(O)=O)CC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1 Show InChI InChI=1S/C21H28N4O4/c1-14(13-18(27)28)12-17(26)24-9-6-21(7-10-24)8-11-25(20(21)29)16-4-2-15(3-5-16)19(22)23/h2-5,14H,6-13H2,1H3,(H3,22,23)(H,27,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143840 ((S)-5-[2-(4-Carbamimidoyl-phenyl)-1-oxo-2,8-diaza-...) Show SMILES C[C@H](CC(O)=O)CC(=O)N1CCC2(CCN(C2=O)c2ccc(cc2)C(N)=N)CC1 Show InChI InChI=1S/C21H28N4O4/c1-14(13-18(27)28)12-17(26)24-9-6-21(7-10-24)8-11-25(20(21)29)16-4-2-15(3-5-16)19(22)23/h2-5,14H,6-13H2,1H3,(H3,22,23)(H,27,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair