BDBM50143847 5-[2-(4-Carbamimidoyl-phenyl)-3-oxo-2,8-diaza-spiro[4.5]dec-8-yl]-5-oxo-3-phenyl-pentanoic acid::CHEMBL64355

SMILES: NC(=N)c1ccc(cc1)N1CC2(CC1=O)CCN(CC2)C(=O)CC(CC(O)=O)c1ccccc1

InChI Key: InChIKey=OTQPSOHVLSUEKO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50143847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143847 (5-[2-(4-Carbamimidoyl-phenyl)-3-oxo-2,8-diaza-spir...) Show SMILES NC(=N)c1ccc(cc1)N1CC2(CC1=O)CCN(CC2)C(=O)CC(CC(O)=O)c1ccccc1 Show InChI InChI=1S/C26H30N4O4/c27-25(28)19-6-8-21(9-7-19)30-17-26(16-23(30)32)10-12-29(13-11-26)22(31)14-20(15-24(33)34)18-4-2-1-3-5-18/h1-9,20H,10-17H2,(H3,27,28)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Tested for inhibition of the binding of fibrinogen to purified human GPIIb-IIIa in a 96-well format (ELISA assay)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50143847 (5-[2-(4-Carbamimidoyl-phenyl)-3-oxo-2,8-diaza-spir...) Show SMILES NC(=N)c1ccc(cc1)N1CC2(CC1=O)CCN(CC2)C(=O)CC(CC(O)=O)c1ccccc1 Show InChI InChI=1S/C26H30N4O4/c27-25(28)19-6-8-21(9-7-19)30-17-26(16-23(30)32)10-12-29(13-11-26)22(31)14-20(15-24(33)34)18-4-2-1-3-5-18/h1-9,20H,10-17H2,(H3,27,28)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of platelet aggregation induced by 20 microM adenosine 5-diphosphate (ADP) in citrated human platelet rich plasma (h-PRP)				J Med Chem 47: 2037-61 (2004) Article DOI: 10.1021/jm030354b BindingDB Entry DOI: 10.7270/Q2FQ9W1H
					More data for this Ligand-Target Pair