BDBM50143914 (3-Cyclohexyl-ureido)-acetic acid::2-(3-cyclohexylureido)acetic acid::CHEMBL66380::N-[(CYCLOHEXYLAMINO)CARBONYL]GLYCINE

SMILES: OC(=O)CNC(=O)NC1CCCCC1

InChI Key: InChIKey=NVORCMBCUHQRDL-UHFFFAOYSA-N

Data: 4 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50143914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50143914 ((3-Cyclohexyl-ureido)-acetic acid | 2-(3-cyclohexy...) Show SMILES OC(=O)CNC(=O)NC1CCCCC1 Show InChI InChI=1S/C9H16N2O3/c12-8(13)6-10-9(14)11-7-4-2-1-3-5-7/h7H,1-6H2,(H,12,13)(H2,10,11,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against mouse soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143914 ((3-Cyclohexyl-ureido)-acetic acid | 2-(3-cyclohexy...) Show SMILES OC(=O)CNC(=O)NC1CCCCC1 Show InChI InChI=1S/C9H16N2O3/c12-8(13)6-10-9(14)11-7-4-2-1-3-5-7/h7H,1-6H2,(H,12,13)(H2,10,11,14)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant soluble Epoxide hydrolase				Bioorg Med Chem Lett 16: 5439-44 (2006) Article DOI: 10.1016/j.bmcl.2006.07.073 BindingDB Entry DOI: 10.7270/Q2183643
					More data for this Ligand-Target Pair				3D Structure (crystal)
Soluble epoxide hydrolase (sEH) (Mus musculus (Mouse))	BDBM50143914 ((3-Cyclohexyl-ureido)-acetic acid | 2-(3-cyclohexy...) Show SMILES OC(=O)CNC(=O)NC1CCCCC1 Show InChI InChI=1S/C9H16N2O3/c12-8(13)6-10-9(14)11-7-4-2-1-3-5-7/h7H,1-6H2,(H,12,13)(H2,10,11,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of mouse recombinant soluble Epoxide hydrolase				Bioorg Med Chem Lett 16: 5439-44 (2006) Article DOI: 10.1016/j.bmcl.2006.07.073 BindingDB Entry DOI: 10.7270/Q2183643
					More data for this Ligand-Target Pair
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50143914 ((3-Cyclohexyl-ureido)-acetic acid | 2-(3-cyclohexy...) Show SMILES OC(=O)CNC(=O)NC1CCCCC1 Show InChI InChI=1S/C9H16N2O3/c12-8(13)6-10-9(14)11-7-4-2-1-3-5-7/h7H,1-6H2,(H,12,13)(H2,10,11,14)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of California-Davis Curated by ChEMBL					Assay Description Tested for 50 % inhibitory concentration against human soluble epoxide hydrolase (sEH)				J Med Chem 47: 2110-22 (2004) Article DOI: 10.1021/jm030514j BindingDB Entry DOI: 10.7270/Q29Z94BM
					More data for this Ligand-Target Pair				3D Structure (crystal)