null
SMILES: CC(C)(C)c1ccc(cc1)C(Oc1ccc(cc1)C(=O)NCC(O)C(O)=O)C(=O)Nc1ccc(cc1)-c1ccccc1
InChI Key: InChIKey=QETNPKWOLZTWCI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glucagon receptor (Homo sapiens (Human)) | BDBM50144010 (3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 112 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro binding affinity against human glucagon receptor (h-GlucR) was determined | Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 1/2/3/4/5/6/7/8/9 (Homo sapiens (Human)) | BDBM50144010 (3-{4-[(Biphenyl-4-ylcarbamoyl)-(4-tert-butyl-pheny...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro inhibitory activity against glucagon induced human adenylate cyclase | Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH | |||||||||||
More data for this Ligand-Target Pair |