BDBM50144013 3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethoxymethyl-phenylcarbamoyl)-ethyl]-benzoylamino}-propionic acid::CHEMBL62531

SMILES: CC(C)(C)c1ccc(cc1)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(COC(F)(F)F)cc1

InChI Key: InChIKey=QLDLIGJRIJWKFV-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144013   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase (Homo sapiens (Human))	BDBM50144013 (3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...) Show SMILES CC(C)(C)c1ccc(cc1)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(COC(F)(F)F)cc1 Show InChI InChI=1S/C31H33F3N2O5/c1-30(2,3)24-12-10-22(11-13-24)26(18-20-4-8-23(9-5-20)28(39)35-17-16-27(37)38)29(40)36-25-14-6-21(7-15-25)19-41-31(32,33)34/h4-15,26H,16-19H2,1-3H3,(H,35,39)(H,36,40)(H,37,38)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against glucagon induced human adenylate cyclase				Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50144013 (3-{4-[2-(4-tert-Butyl-phenyl)-2-(4-trifluoromethox...) Show SMILES CC(C)(C)c1ccc(cc1)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)C(=O)Nc1ccc(COC(F)(F)F)cc1 Show InChI InChI=1S/C31H33F3N2O5/c1-30(2,3)24-12-10-22(11-13-24)26(18-20-4-8-23(9-5-20)28(39)35-17-16-27(37)38)29(40)36-25-14-6-21(7-15-25)19-41-31(32,33)34/h4-15,26H,16-19H2,1-3H3,(H,35,39)(H,36,40)(H,37,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human glucagon receptor (h-GlucR) was determined				Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH
					More data for this Ligand-Target Pair