BDBM50144014 3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin-1-yl)-3-oxo-propyl]-benzoylamino}-propionic acid::CHEMBL64290

SMILES: CCN1CCN(CC1)C(=O)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)c1ccc(cc1)C(C)(C)C

InChI Key: InChIKey=VBTQLJRYVDHQCK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50144014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase (Homo sapiens (Human))	BDBM50144014 (3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin...) Show SMILES CCN1CCN(CC1)C(=O)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C29H39N3O4/c1-5-31-16-18-32(19-17-31)28(36)25(22-10-12-24(13-11-22)29(2,3)4)20-21-6-8-23(9-7-21)27(35)30-15-14-26(33)34/h6-13,25H,5,14-20H2,1-4H3,(H,30,35)(H,33,34)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against glucagon induced human adenylate cyclase				Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH
					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50144014 (3-{4-[2-(4-tert-Butyl-phenyl)-3-(4-ethyl-piperazin...) Show SMILES CCN1CCN(CC1)C(=O)C(Cc1ccc(cc1)C(=O)NCCC(O)=O)c1ccc(cc1)C(C)(C)C Show InChI InChI=1S/C29H39N3O4/c1-5-31-16-18-32(19-17-31)28(36)25(22-10-12-24(13-11-22)29(2,3)4)20-21-6-8-23(9-7-21)27(35)30-15-14-26(33)34/h6-13,25H,5,14-20H2,1-4H3,(H,30,35)(H,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro binding affinity against human glucagon receptor (h-GlucR) was determined				Bioorg Med Chem Lett 14: 2047-50 (2004) Article DOI: 10.1016/j.bmcl.2004.02.056 BindingDB Entry DOI: 10.7270/Q2XS5TTH
					More data for this Ligand-Target Pair