BDBM50144090 CHEMBL62563::[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazin-1-yl]-[4-(imino-morpholin-4-yl-methyl)-phenyl]-methanone

SMILES: Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCOCC1

InChI Key: InChIKey=JMQKFPYHLCESRV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144090   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144090 (CHEMBL62563 | [4-(6-Bromo-naphthalene-2-sulfonyl)-...) Show SMILES Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCOCC1 Show InChI InChI=1S/C26H27BrN4O4S/c27-23-7-5-22-18-24(8-6-21(22)17-23)36(33,34)31-11-9-30(10-12-31)26(32)20-3-1-19(2-4-20)25(28)29-13-15-35-16-14-29/h1-8,17-18,28H,9-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair