BDBM50144095 CHEMBL65544::[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazin-1-yl]-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenyl]-methanone

SMILES: Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C1=NCCN1

InChI Key: InChIKey=OBCUHLZHIJDNHA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144095   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144095 (CHEMBL65544 | [4-(6-Bromo-naphthalene-2-sulfonyl)-...) Show SMILES Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C1=NCCN1 |t:32| Show InChI InChI=1S/C24H23BrN4O3S/c25-21-7-5-20-16-22(8-6-19(20)15-21)33(31,32)29-13-11-28(12-14-29)24(30)18-3-1-17(2-4-18)23-26-9-10-27-23/h1-8,15-16H,9-14H2,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair