BDBM50144107 CHEMBL446398::[4-(6-Bromo-naphthalene-2-sulfonyl)-piperazin-1-yl]-[4-(imino-pyrrolidin-1-yl-methyl)-phenyl]-methanone

SMILES: Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCC1

InChI Key: InChIKey=DIGYVARAECKUFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144107 (CHEMBL446398 | [4-(6-Bromo-naphthalene-2-sulfonyl)...) Show SMILES Brc1ccc2cc(ccc2c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(=N)N1CCCC1 Show InChI InChI=1S/C26H27BrN4O3S/c27-23-9-7-22-18-24(10-8-21(22)17-23)35(33,34)31-15-13-30(14-16-31)26(32)20-5-3-19(4-6-20)25(28)29-11-1-2-12-29/h3-10,17-18,28H,1-2,11-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair