BDBM50144116 CHEMBL292941::{4-(5-Chloro-1H-indole-2-sulfonyl)-1-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-benzoyl]-piperazin-2-yl}-acetic acid

SMILES: CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(O)=O)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=VSOQUGPDPQENAD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144116 (CHEMBL292941 | {4-(5-Chloro-1H-indole-2-sulfonyl)-...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(O)=O)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1 |c:4| Show InChI InChI=1S/C25H26ClN5O5S/c1-29-9-8-27-24(29)16-2-4-17(5-3-16)25(34)31-11-10-30(15-20(31)14-23(32)33)37(35,36)22-13-18-12-19(26)6-7-21(18)28-22/h2-7,12-13,20,28H,8-11,14-15H2,1H3,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair