BDBM50144128 2-{4-(5-Chloro-1H-indole-2-sulfonyl)-1-[4-(1-methyl-4,5-dihydro-1H-imidazol-2-yl)-benzoyl]-piperazin-2-yl}-1-piperidin-1-yl-ethanone::CHEMBL291429

SMILES: CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCCCC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=BYTQLBBGDDKNNJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50144128   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50144128 (2-{4-(5-Chloro-1H-indole-2-sulfonyl)-1-[4-(1-methy...) Show SMILES CN1CCN=C1c1ccc(cc1)C(=O)N1CCN(CC1CC(=O)N1CCCCC1)S(=O)(=O)c1cc2cc(Cl)ccc2[nH]1 |c:4| Show InChI InChI=1S/C30H35ClN6O4S/c1-34-14-11-32-29(34)21-5-7-22(8-6-21)30(39)37-16-15-36(20-25(37)19-28(38)35-12-3-2-4-13-35)42(40,41)27-18-23-17-24(31)9-10-26(23)33-27/h5-10,17-18,25,33H,2-4,11-16,19-20H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Millennium Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against Coagulation factor X was determined				Bioorg Med Chem Lett 14: 2073-8 (2004) Article DOI: 10.1016/j.bmcl.2004.02.049 BindingDB Entry DOI: 10.7270/Q2P84B98
					More data for this Ligand-Target Pair